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Search Results for " flt3 ligand "
Targets Recommended: FLT Tyrosine Kinases

3

抑制剂 & 化合物

7

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T71857 GTP-14564

FLT; Tyrosine Kinases Angiogenesis; Tyrosine Kinase/Adaptors
GTP-14564是一种新型酪氨酸激酶抑制剂,对 wt-FLT3和ITD-FLT3也具有抑制作用。GTP-14564 在 3μ m 处抑制表达 ITD-FLT3 的白细胞介素-3 非依赖性 Ba/F1 的生长,而需要高 30 倍的 GTP-14564 浓度来抑制表达野生型 FLT3 的 Ba/F3FLT3 配体依赖性生长 (wt-FLT3)。
T71400 Quizartinib HCl

Quizartinib, also know as AC220 and AC010220, is an orally available FLT3 / STK1 inhibitor with potential antineoplastic activity. Class III receptor tyrosine kinase inhibitor AC220 selectively inhibits class III receptor tyrosine kinases, including FMS-related tyrosine kinase 3 (FLT3/STK1), colony-stimulating factor 1 receptor (CSF1R/FMS), stem cell factor receptor (SCFR/KIT), and platelet derived growth factor receptors (PDGFRs), resulting in inhibition of ligand-independent leukemic cell pro...
T68497 FI-700

FI-700 is a novel and potent FLT3 inhibitor with promising antileukemia activity. FI-700 showed a potent IC(50) value against FLT3 kinase at 20 nmol/L in an in vitro kinase assay. FI-700 showed selective growth inhibition against mutant FLT3-expressing leukemia cell lines and primary acute myeloid leukemia cells, whereas it did not affect the FLT3 ligand (FL)-driven growth of Wt-FLT3-expressing cells. Oral administration of FI-700 induced the regression of tumors in a s.c. tumor xenograft model ...

化合物

GTP-14564
Cat.No: T71857
Synonym:
Target: FLT, Tyrosine Kinases
Quizartinib HCl
Cat.No: T71400
Synonym:
Target:
FI-700
Cat.No: T68497
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant

FLT3LG,fms related tyrosine kinase 3

Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPK-00125 FLT3 Ligand Protein, Human, Recombinant (hFc)

FLT3LG,FL,Flt3 ligan...

Human HEK293 Cells
Flt3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Ligand Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 44.8 kDa and the accession number is P49771-1.
TMPY-03066 FLT3 Ligand Protein, Mouse, Recombinant (hFc)

Ly72L,Flt3lg,fms related tyrosine kinase <...

Mouse HEK293 Cells
FLT3 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P49772-1.
TMPY-03215 FLT3 Ligand Protein, Human, Recombinant (His)

fms related tyrosine kinase 3 ligand,F...

Human Baculovirus Insect Cells
FLT3 Ligand Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.2 kDa and the accession number is P49771-1.
TMPK-00929 FLT3 Protein, Mouse, Recombinant (hFc)

FL,FLT3LG,Flt3L,SL cytok...

Mouse HEK293 Cells
Flt3 Ligand, also known as FL, is an alpha -helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages.Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. FLT3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 84.78 kDa and the accession number is Q00342.
TMPJ-00123 FLT3LG Protein, Mouse, Recombinant (His)

Fms-related tyrosine kinase 3 ligand (...

Mouse HEK293 Cells
Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and colony stimulating factor. Flt3L synergizes well with a number of other colony stimulating factors and interleukins. Flt3L stimulates the proliferation and differentiation of various blood cell progentiors by activating FLT3.
TMPY-05332 FLT3 Ligand Protein, Rat, Recombinant (His)

fms related tyrosine kinase 3 ligand

Rat Baculovirus Insect Cells
FLT3 Ligand Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is NP_001292868.1.

重组蛋白

FLT3 Ligand Protein, Human, Recombinant
Cat.No: TMPY-06873
Species: Human
Expression System: E. coli
FLT3 Ligand Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00125
Species: Human
Expression System: HEK293 Cells
FLT3 Ligand Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03066
Species: Mouse
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant (His)
Cat.No: TMPY-03215
Species: Human
Expression System: Baculovirus Insect Cells
FLT3 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00929
Species: Mouse
Expression System: HEK293 Cells
FLT3LG Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00123
Species: Mouse
Expression System: HEK293 Cells
FLT3 Ligand Protein, Rat, Recombinant (His)
Cat.No: TMPY-05332
Species: Rat
Expression System: Baculovirus Insect Cells
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